Eudoxie Pepelassi-Kostopoulou

Professor

Department of Periodontology

 

Contact details

Phone: (+30) 210-746-1223
Email: epepela[at]dent.uoa[dot]gr

Mailing Address:
2 Thivon Str, 115 27 Athens, Greece

Profiles and publications

   

Education/ Qualifications

• 1980-1985: Doctor of Dental Surgery, School of Dentistry, National and Kapodistrian University of Athens (NKUA), Greece.
• 1986-1988: Certificate in Periodontology, Case Western Reserve University, USA.
• 1986-1988: Master of Science in Dentistry, Case Western Reserve University, USA.
• 1991-1995: Doctor of Dentistry, Department of Periodontology, School of Dentistry, NKUA

Academic and professional positions held

• 2020-: Professor, Department of Periodontology, School of Dentistry, NKUA.
• 2014-2020: Associate Professor, Department of Periodontology, School of Dentistry, NKUA.
• 2008-2014: Tenured Assistant Professor, Department of Periodontology, School of Dentistry, NKUA.
• 2004-2008: Assistant Professor, Department of Periodontology, School of Dentistry, NKUA.
• 1999-2004: Lecturer, Department of Periodontology, School of Dentistry, NKUA.
• 1988-1999: Clinical Associate, Department of Periodontology, School of Dentistry, NKUA.

Administrative and organizational experience

• 2000-: Coordinator of the Postgraduate Literature Review Seminars.
• 2009-2013 and 2014-: Supervisor at the undergraduate Comprehensive Care Clinic.
• 2015-2017: Associate coordinator of the undergraduate Comprehensive Care Clinic.
• 2000-2009: Coordinator of the Postgraduate Clinic of Periodontology.

Research Grants and Contracts

• “Evaluation of the effect of rhBMP-2,-3 and-7 on human periodontal ligament cells, osseous cells and cementoblasts”. “Th. Koulouridis” Annual research grant of Procter & Gamble Hellas Ltd. Company.
• “Biologic effects of platelet rich plasma (PRP) on gingival fibroblasts originating from patients presenting chronic and aggressive periodontitis”. “Kapodistrias” Research grant, Hellenic Ministry of Education.
• “Evaluation of the recombinant human Transforming growth factor-β1 (rhTGF-β1) on the differentiation of human periodontal ligament cells by using various transferring methods”. “Kapodistrias” Research grant, Hellenic Ministry of Education.
• “Bacteriocins produced by food-related lactic acid bacteria active towards oral pathogens”. Research grant, Hellenic Ministry of Health and Social Solidarity.  
• “Clinical effectiveness of the Colgate ® Sensitive Pro-Relief TM on dentin hypersensitivity in periodontitis patients”. Research grant, Colgate-Palmolive Company.

Awards and Honours

• 2005: Award by the British Society for Disability and Oral Health for the best publication on individuals with special needs. 
• 2005:  “Th. Koulouridis” Award and Annual Grant of Procter & Gamble Hellas Ltd. Company.
• 1981-1985: Scholarship by the State Scholarships Foundation.

Memberships

• European Federation of Periodontology
• American Academy of Periodontology
• American Dental Society of Europe
• International Dental Society of Dentists
• Hellenic Dental Association
• Hellenic Society of Odontostomatological Research
• Hellenic Society of Periodontology
• Hellenic Association of Periodontists
• Hellenic Prosthodontic Society

Research Theses - Books

• Pepelassi E.A. (1988) Periodontal evaluation of tricalcium phosphate - doxycycline composite graft in the treatment of furcation defects. Thesis for the Master of Science in Dentistry, Case Western Reserve University.
• Pepelassi E.A. (1994) Comparative evaluation of radiographic and surgical findings  in periodontal osseous defects. Thesis for the Doctor of Dentistry Degree, National and Kapodistrian University of Athens.
• Pepelassi E.A. (2012) Experimental induction of periodontitis and diabetes mellitus in Wistar rats: Histometric and biochemical analysis. E.A. Pepelassi. “Monograph” Thesis, National and Kapodistrian University of Athens.
• Athanasouli Th., Nikolatou-Galiti O., Tzoutzas I., Kavadia K., Pepelassi E. (2007) The oral health and the oncology patient. Publisher: Medical Editions Litsas, Athens.

Selected publications in scientific journals

• Pepelassi E., Bissada N.F., Greenwell H., Farah C.F. Doxycycline - tricalcium phosphate composite graft facilitates osseous healing in advanced periodontal furcation defects. J Periodontol 1991; 62: 106-115.
• Pepelassi E., Diamanti-Kipioti A. Selection of the most accurate method of conventional radiography for the assessment of periodontal osseous destruction. J Clin Periodontol 1997; 24: 557-567.
• Pepelassi E.A., Tsiklakis K., Diamanti-Kipioti A. Radiographic detection and assessment of the periodontal endosseous defects. J Clin Periodontol 2000; 27:224-230.
• Antonadou D., Pepelassi M., Synodinou M., Puglisi M., Throuvalas N. Prophylactic use of aminofostine to prevent radiochemotherapy induced mucositis and xerostomia in head – and – neck cancer. Int J Radiat Oncol Biol Phys 2002; 52(3): 739-747.
• Tsami A., Pepelassi E., Gizani S., Komboli M., Papagiannoulis L., Mantzavinos M. Oral hygiene and periodontal treatment needs in young individuals with special needs in Greece. JDOH 2004; 5(1): 57-64.
• Pepelassi E., Tsami A., Komboli M. Root caries in periodontally treated patients in relation to their compliance with suggested periodontal maintenance intervals. Compend Contin Educ Dent  2005; 26: 835-845.
• Kavvadia K., Pepelassi E., Alexandridis C.,  Arkadopoulou A., Polyzois G., Tossios K. Gingival fibromatosis and significant tooth eruption delay in an 11 years old male: 30 months follow-up. Int J Paediatr Dent 2005; 15: 294-302.
• Dereka X.E., Markopoulou C.E., Mamalis A., Pepelassi E., Vrotsos I.A. Time-and dose-dependent mitogenic effect of bFGF combined with different bone graft materials. An in vitro study. Clin Oral Implants Res 2006; 17(5): 554-559.
• Pepelassi E.A., Markopoulou C.E., Dereka X.E., Mamalis A.A., Vrotsos I.A.,  Koutsilieris M. Platelet-rich plasma effect on periodontally affected human gingival fibroblasts: an in vitro study. J Int Acad Periodontol  2009; 11: 160-168.
• Tsami A., Pepelassi E., Kodovazenitis G., Komboli M. Parameters affecting tooth loss during periodontal maintenance in a Greek population. JADA  2009; 140: 1100-1107.
• Markou N., Pepelassi E., Vavouraki H., Stamatakis H., Nikolopoulos G., Vrotsos I., Tsiklakis K. Treatment of periodontal endosseous defects with platelet-rich plasma alone or in combination with demineralized freeze-dried bone allograft: A comparative clinical trial. J Periodontol 2009; 80: 1911-1919.
• Kotsovilis S., Markou N., Pepelassi E., Nikolidakis D. The adjunctive use of platelet-rich plasma in the therapy of periodontal intraosseous defects: a systematic review. J Periodont Res 2010; 45: 428-443.
• Markou N., Pepelassi E., Kotsovilis S., Vrotsos I., Vavouraki H., Stamatakis H.C. The use of platelet-rich plasma combined with demineralized freeze-dried bone allograft in the treatment of periodontal endosseous defects: a report of two clinical cases. JADA 2010; 141(8): 967-978.
• Mouzakiti E., Pepelassi E., Fanourakis G., Markopoulou C., Tseleni-Balafouta S., Vrotsos I.  The effect of smoking on the mRNA expression of MMPs and TIMP-1 in untreated chronic periodontitis patients: A cross-sectional study. J Periodont Res 2011; 46 (5): 576-583.
• Markopoulou C.E., Dereka X.E., Vavouraki H.N., Pepelassi E.A., Mamalis A.A., I.K. Karoussis, Vrotsos I.A. Effect of rhTGF-β1 combined with bone grafts on human periodontal cell differentiation. Growth Factors 2011; 29(1): 14-20.
• Patsouri A., Mavrogiannea A., Pepelassi E., Gaintantzopoulou M., Kakaboura A. Clinical effectiveness of a desensitizing system on dentin hypersensitivity in periodontitis patients. Am J Dent 2011; 24(2): 85-92.
• Plessas A., Pepelassi E. Dental and periodontal complications of lip and tongue piercing: Prevalence and influencing factors. Aust Dent J 2012; 57: 71–78.
• Pepelassi E., Nicopoulou-Karayianni K.,  Archontopoulou A.D., Mitsea A.,  Kavadella A., Tsiklakis K., Vrotsos I., Devlin H., Horner K.. The relationship between osteoporosis and periodontitis in women aged 45–70 years. Oral Dis 2012; 18 (4): 353-359.
• Mouzakiti E., Pepelassi  E., Fanourakis G., Markopoulou C., Tseleni-Balafouta S.,  Vrotsos I. Expression of MMPs and TIMP-1 in smoker and nonsmoker chronic periodontitis patients before and after periodontal treatment. J Periodont Res 2012; 47(4): 532-542.
• Xynogala I., Pepelassi E., Perrea D., Agrogiannis G., Pantopoulou A., Patsouris E.,  Vrotsos I.  Adiponectin and interleukin-6 levels in insulin-treated diabetic rats with experimental periodontitis. Braz Oral Res 2012; 26(1): 71–76.
• Pepelassi E., Xynogala I., Perrea D., Agrogiannis G., Pantopoulou A., Patsouris E., Vrotsos I. Histometric Assessment of the Effect of Diabetes Mellitus on Experimentally Induced Periodontitis in Rats. J Int Acad Periodontol  2012; 14(2): 35-41.
• Zoumpopoulou G., Pepelassi E., Papaioannou W., Georgalaki M., Maragkoudakis P.A., Tarantilis P., Tsakalidou E., Papadimitriou K. Incidence of bacteriocins produced by food-related lactic acid bacteria active towards oral pathogens. Int J Mol Sci  2013; 14(3): 4640-4654.
• Pepelassi E, Rahiotis C, Peponi E, Kakaboura A, Vrotsos I. Effectiveness of an in-office arginine–calcium carbonate paste on dentine hypersensitivity in periodontitis patients: a double-blind, randomized controlled trial. J Clin Periodontol 2015; 42: 37–45.
• Alexandridi F, Tsantila S, Pepelassi E. Smoking cessation and response to periodontal treatment. Aust Dent J 2018; 63 (2):140-149.
• Vassilopoulos S, Bobetsis Y, Mastoris M, Pepelassi E, Karagianni K. Detection accuracy of bone defects depending on exposure settings of cone beam computed tomography. Int J Periodontics Restorative Dent (accepted for publication 20/2/2019)

Areas of scientific interest

• Periodontal regeneration
• Experimental periodontitis
• Biology of the periodontal tissues
• Implantology