Home[English] » Faculty and Staff » Dental faculty » Sklavounou Alexandra

Alexandra Sklavounou-Andrikopoulou

Professor, Head of the Dept. of Oral Medicine & Pathology


Phone: (+30) 210-746-1002
Email: asklavou[at]dent.uoa[dot]gr

Mailing Address:
2 Thivon Str, 115 27, Goudi, Athens, Greece

Ελληνική Έκδοση English Version

Education / Qualifications

  • DDS, Dental School, National and Kapodistrian University of Athens, Greece 1976
  • MSc in Oral Biology, University of Minnesota, USA 1979
  • PhDin Oral Medicine & Pathology,Dental School,National and Kapodistrian University of Athens, Greece 1981
  • Postdoctoral research fellow, Department of Immunology and Parasitic Diseases, Pasteur Institute, Athens 1991-2

Academic and professional positions held

  • Research Assistant in Oral Medicine & Pathology, Dental School, National and Kapodistrian University of Athens, 1980
  • Tenured Lecturer in Oral Medicine & Pathology, Dental School, National and Kapodistrian University of Athens, 1984
  • Tenured Assistant Professor in Oral Medicine & Pathology, Dental School, National and Kapodistrian University of Athens, 1985
  • Associate Professor in Oral Medicine & Pathology, Dental School, National and Kapodistrian University of Athens, 2000
  • Head of the Dept. of Oral Medicine & Pathology Dental School, National and Kapodistrian University of Athens, 2006-date 
  • Professor in Oral Medicine & Pathology, Dental School, National and Kapodistrian University of Athens, 2007-date

Academic responsibilities

  • Director of Oral Medicine Clinic of Evangelismos General Hospital, Athens 2001- date
  • Member of the Postgraduate Curriculum Committee, Dental School, University of Athens, 2007-date
  • Director of the postgraduate program in Oral Medicine and Pathology, Dental School, University of Athens, 2007-date
  • Director of the undergraduate program in Oral Medicine and Pathology, Dental School, University of Athens, 2007-date
  • President of the Undergraduate Curriculum Committee, Dental School, University of Athens, 2009-2011
  • President of the Library Committee, Dental School, University of Athens, 2009-2011
  • Supervisor in 6 PhD dissertations and 10 MSc theses. Member in 18 PhD advisory committees and 33 MSc advisory committees, Postgraduate Program, Dental School, University of Athens

Professional responsibilities

  • Member of the Scientific Committee, Athens Dental Society, 2002-2011
  • Memberof  the Organizing Committee of the 7th Congress of the European Association of Oral Medicine-EAOM, Berlin 2004
  • Member of  the Organizing Committee of the 26th Hellenic Dental Congress, Athens 2006
  • Presidentof  the Organizing Committee of the 11th and 12th Dental Students’ Congress, Dental School, University of Athens, 2006 & 2008
  • President of the Scientific Committee of the Athens Dental Society, 2006-2008
  • Presidentof the Hellenic Society of Oral Medicine and Pathology, 2007-2012
  • President of the Organizing Committee of the 1st Congress of the Hellenic Society of Oral Medicine and Pathology, Athens 2009
  • Board Member of the European Association of Oral Medicine, 2009-date
  • President of the Organizing Committee of the 11th Biennial Congress of the European Association of Oral Medicine, Athens 2012
  • President of the Organizing Committee of the 2nd Congress of the Hellenic Society of Oral Medicine and Pathology, Athens 2012
  • Director of the HPV-research group of the Hellenic Society for the research and treatment of papilloma virus (HPV) - Section HPV and Oral Medicine, 2012
  • Guest-editor of the International Journal of Dentistry as a representative of Europe, 2012
  • Elected Board Member of the Hellenic Dental Association, 2005-date

Research Grants and Contracts

  • Evaluation of apoptosis-regulating proteins in oral lichen planus, 2000
  • Serum circulating levels of apoptosis-related molecules in oral lichen planus, 2004
  • Evaluation of the apoptotic molecules Fas, TRΑIL, FLIP, Caspace 8 in the oral squamous cell carcinoma, 2006
  • The oncogenic role of STAT3 in oral squamous cell carcinoma [Irakleitos ΙΙ], 2011-2013
  • Correlation of HPV infection with TLR4 and TLR9 –dependent immune response and the expression of interferon IFN-α and IFN-β in squamous cell carcinoma of the tongue [partly sponsored by VIANEX Pharmaceutical Company], 2012
  • Research project granted by the National and Kapodistrian University of Athens:
  • Investigation of expression, activation and interaction of signaling pathways MAPK and STAT3 in oral squamous cell carcinoma, 2008-2009

Awards and Honours

  • 1st  highest ranking in the Panhellenic entrance exams, Dental School, University of Athens, Greece 1971
  • Scholarship from the State Scholarships Foundation for the academic years 1971-1975
  • Dental Degree with Honors (Magna cum laude), Dental School, University of Athens, 1976
  • Scholarship from the French Government for Doctorate postgraduate studies (Doctorat d’ Etat) in Oral Medicine and Pathology, Paris V University of Paris, France 1976
  • Scholarship from the University of Minnesota, USA for MSc graduate studies, 1977-79
  • Award from the Dental School, University of Athens for PhD thesis, 1981
  • 1st award, 26th Hellenic Dental Congress, Athens 2006
  • 1st award, 5th Hellenic Congress of Medical Biopathology (Microbiology), Athens 2008
  • 1st award, 29th Hellenic Dental Congress, Athens 2009
  • Hamilton B.G. Robinson Prize,  for the best Oral and Maxillofacial Pathology scientific paper published in Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontics, 2009
  • Young Scientist/Clinician Awards, 10th Biennial Conference of European Association of Oral Medicine, London 2010
  • Waldron Award, 65th Annual Meeting and Continuing Education Program of American Academy of Oral and Maxillofacial Pathology, San Juan, Puerto Rico 2011
  • Honorary award from the Society for the Promotion of Education and Learning, Arsakeia - Tositseia Schools, 2011
  • Honorary Member of Romanian Oral Medicine Association, 2012

Memberships

  • American Academy of Oral and Maxillofacial Pathology
  • International Association of Oral Pathologists
  • European Association of Oral Medicine (EAOM)
  • Hellenic Association of Supportive Care of the Oral Cavity in Cancer
  • Hellenic Society of Odontostomatological Research
  • Hellenic Association of Immunology
  • Hellenic Society for the research and treatment of papilloma virus (HPV)
  • Hellenic Society of Oral Medicine and Pathology
  • Balkan Stomatological Society
  • Hellenic Society of Autoimmune Diseases

Research Theses - Books

  • MSc thesis: Calcium and total protein synthesis in skin fibroblasts from patients with cystic fibrosis and control subjects, University of Minnesota 1979
  • MSc thesis: Adherence of certain oral streptococci to keratinized human oral epithelial cells, University of Minnesota 1979
  • PhD Dissertation: Serum immunoglobulins and complement C3 in oral lichen planus, Athens 1981
  • Research monograph: Serum physical auto-antibodies in oral lichen planus, Pasteur Institute, Athens 1989
  • Research monograph: Peripheral blood mononuclear cell function and serum cytokines in oral lichen planus, Pasteur Institute, Athens 1993
  • Interactive CD: “Diagnosis and management of common oral mucosal diseases”, Athens 2006
  • Chapter: “HPV-related lesions of the oral cavity”, in Emmanuel Diakomanolis’ Textbook “Colposcopy and Pathology of the female lower genital tract”, Paschalides P. Ch. Editor 2010

Selected publications in scientific journals

  • Sklavounou-Andrikopoulou A, Chrysomali E, Iakovou M, Garinis GA, Karameris A. Elevated serum levels of the apoptosis related molecules TNF-a, Fas/Apo-I and Bcl-2 in oral lichen planus. J Oral Pathol Med 2004; 33: 386-90
  • Sklavounou A, Toutouzas I, Tsorfolias A, Tseleni Balafouta S.  Immunohistochemical study of Fas, TRAIL, FLIP, procaspace 8 and activated caspase 8 in oral squamous cell carcinoma. Oral Diseases (suppl.) 2006; 12:6
  • Mitrou GK, Tosios KI, Kyroudi A, Sklavounou A. Odontogenic keratocyst express vascular endothelial growth factor: An immunohistochemical study. J Oral Pathol Med 2009; 38(5): 470-5
  • Nikitakis NG, Scheper MA, Papanicolaou VS, Sklavounou A, Sauk JJ. Immunohistochemical expression of the oncogenic molecules active Stat3 and survivin in benign and malignant salivary gland tumors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009; 107:837-43
  • Houpis CH, Tosios KI, Papavasileiou D, Christopoulos PG, Koutlas IG, Sklavounou A, Alexandridis C. Parathyroid hormone-related peptide (PTHrP), parathyroid hormone/parathyroid hormone-related peptide receptor 1 (PTHR1), and MSX1 protein are expressed in central and peripheral giant cell granulomas of the jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 109(3): 415-2
  • Tosios KI, Nikolakis M, Prigkos A, Diamanti S, Sklavounou A. Nerve cell bodies and small ganglia in the connective tissue stroma of human submandibular glands. Neuroscience Letters 2010; 475(1): 53–5
  • Chatzistamou I, Sklavounou A, Kittas  C, Klianjenko J. Prognostic significance of tumor shape and stromal chronic inflammation in squamous cell carcinomas of the mobile tongue. J Oral Pathol Med 2010; 39(9):667-71.
  • Chatzistamou I, Trimis G, Dioufa N, Sklavounou A, Kittas  C, Papavassiliou AG, Kiaris H. Expression of  p21waf1/Cip1 in stromal fibroblasts of oral cancers regulates smooth-muscle actin a and cell migration. Cell Oncol 2011; 34(5):483-8
  • Babaloukas G., Tentolouris N., Liatis S., Sklavounou A., Perrea D. Evaluation of three methods for retrospective correction of vignetting on medical microscopy images utilizing two open source software tools. Microscopy 2011; 244: 320-324
  • Tosios KI, Prountzos N, Katsoulas N, Koutlas IG, Sklavounou-Andrikopoulou A. Melan-A/Mart-1- or HMB-45-positive melanocytes are not present in calcifying cystic odontogenic tumors (calcifying odontogenic cysts): a study in 13 Caucasian patients. J Oral Sci 2012; 54(1): 33-8
  • Karathanasi V, Tosios KI, Nikitakis NG, Piperi E., Koutlas I, Trimis G, Sklavounou A. TGF-β1, Smad-2/-3, Smad-1/-5/-8, and Smad-4 signaling factors are expressed in ameloblastomas, adenomatoid odontogenic tumors, and calcifying cystic odontogenic tumors: an immunohistochemical study. J Oral Pathol Med. 2012 Nov 15. Doi: 10.1111/jop. 12016. [Epub ahead of print]

Areas of scientific interest

  • Immunology/Immunopathology (Pathogenesis of immune-mediated oral diseases)
  • Oral potentially malignant disorders and squamous cell carcinoma (HPV-infection, immunohistochemical, molecular markers)
  • Oral manifestations of systemic diseases (diagnosis and management)

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