Home[English] » Faculty and Staff » Dental faculty » Pepelasi-Kostopoulou Evdoxia

Eudoxie Pepelassi

Associate Professor

Phone: (+30) 210-746-1223
Email:epepela[at]dent.uoa[dot]gr

Mailing Address:
2 Thivon Str, 115 27, Goudi, Athens, Greece

Ελληνική Έκδοση English Version

Education/ Qualifications

  • 1980-1985: Doctor of Dental Surgery, School of Dentistry, National and Kapodistrian University of Athens, Greece.
  • 1986-1988: Certificate in Periodontology, Case Western Reserve University, USA.
  • 1986-1988: Master of Science in Dentistry, Case Western Reserve University, USA.
  • 1991-1995: Doctor of Dentistry, Department of Periodontology, School of Dentistry, National and Kapodistrian University of Athens, Greece.

Academic and professional positions held

  • 1988-1999: Clinical and Research Associate, Department of Periodontology, School of Dentistry, National and Kapodistrian University of Athens, Greece.
  • 1999-2004: Lecturer, Department of Periodontology, School of Dentistry, National and Kapodistrian University of Athens, Greece.
  • 2004-2008: Assistant Professor, Department of Periodontology, School of Dentistry, National and Kapodistrian University of Athens, Greece.
  • 2008-2014: Tenured Assistant Professor, Department of Periodontology, School of Dentistry, National and Kapodistrian University of Athens, Greece.
  • 2014-: Associate Professor Department of Periodontology, School of Dentistry, National and Kapodistrian University of Athens, Greece.

Academic and professional responsibilities

  • 2000-2009: Coordinator of the Postgraduate Clinic of Periodontology.
  • 2000-: Coordinator of the Literature Review Seminars (PERIO 453.1-453.3) of the Postgraduate Program in Periodontology.
  • 2009-2013: Supervisor at the undergraduate Comprehensive Care Clinic.

Research Grants and Contracts

  • “Evaluation of the effect of rhBMP-2,-3 and-7 on human periodontal ligament cells, osseous cells and cementoblasts”. “Th. Koulouridis” Annual research grant of Procter & Gamble Hellas Ltd. Company.
  • “Biologic effects of platelet rich plasma (PRP) on gingival fibroblasts originating from patients presenting chronic and aggressive periodontitis”. “Kapodistrias” Research grant, Hellenic Ministry of Education.
  • “Evaluation of the recombinant human Transforming growth factor-β1 (rhTGF-β1) on the differentiation of human periodontal ligament cells by using various transferring methods”. “Kapodistrias” Research grant, Hellenic Ministry of Education.
  • “Exploration of the existence of bacteriocins against bacteria implicated in periodontitis”. Research grant, Hellenic Ministry of Health and Social Solidarity.  
  • “Clinical effectiveness of the Colgate ® Sensitive Pro-Relief TM on dentin hypersensitivity in periodontitis patients”. Research grant, Colgate-Palmolive Company.

Scholarships and Awards

  • 1981-1985: Scholarship by the State Scholarships Foundation.
  • 2005:  “Th. Koulouridis” Award and Annual Grant of Procter & Gamble Hellas Ltd. Company.
  • 2005: Award by the British Society for Disability and Oral Health for the best publication on individuals with special needs. 

Memberships

  • European Federation of Periodontology
  • American Academy of Periodontology
  • American Dental Society of Europe
  • International Dental Society of Dentists
  • Hellenic Dental Association
  • Hellenic Society of Odontostomatological Research
  • Hellenic Society of Periodontology
  • Hellenic Association of Periodontists
  • Hellenic Prosthodontic Society
  • Hellenic Society of Osseointegration

Research Theses - Books

  • Pepelassi E.A. (1988) Periodontal evaluation of tricalcium phosphate - doxycycline composite graft in the treatment of furcation defects. Thesis for the Master of Science in Dentistry, Case Western Reserve University.
  • Pepelassi E.A. (1994) Comparative evaluation of radiographic and surgical findings  in periodontal osseous defects. Thesis for the Doctor of Dentistry Degree, National and Kapodistrian University of Athens.
  • Pepelassi E.A. (2012) Experimental induction of periodontitis and diabetes mellitus in Wistar rats: Histometric and biochemical analysis. E.A. Pepelassi. “Monograph” Thesis, National and Kapodistrian University of Athens.
  • Athanasouli Th., Nikolatou-Galiti O., Tzoutzas I., Kavadia K., Pepelassi E. (2007) The oral health and the oncology patient. Publisher: Medical Editions Litsas, Athens.

Selected publications in scientific journals

  1. Pepelassi E., Bissada N.F., Greenwell H., Farah C.F. Doxycycline - tricalcium phosphate composite graft facilitates osseous healing in advanced periodontal furcation defects. Journal of Periodontology 1991; 62: 106-115.
  2. Pepelassi E., Diamanti-Kipioti A. Selection of the most accurate method of conventional radiography for the assessment of periodontal osseous destruction. Journal of Clinical Periodontology 1997; 24: 557-567.
  3. Pepelassi E.A., Tsiklakis K., Diamanti-Kipioti A. Radiographic detection and assessment of the periodontal endosseous defects. Journal of Clinical Periodontology 2000; 27:224-230.
  4. Antonadou D., Pepelassi M., Synodinou M., Puglisi M., Throuvalas N. Prophylactic use of aminofostine to prevent radiochemotherapy induced mucositis and xerostomia in head – and – neck cancer. International Journal of Radiation Oncology Biology Physics 2002; 52(3): 739-747.
  5. Tsami A., Pepelassi E., Gizani S., Komboli M., Papagiannoulis L., Mantzavinos M. Oral hygiene and periodontal treatment needs in young individuals with special needs in Greece. Journal of Disability and Oral Health 2004; 5(1): 57-64.
  6. Pepelassi E., Tsami A., Komboli M. Root caries in periodontally treated patients in relation to their compliance with suggested periodontal maintenance intervals. Compendium of Continuing Education in Dentistry 2005; 26: 835-845.
  7. Kavvadia K., Pepelassi E., Alexandridis C.,  Arkadopoulou A., Polyzois G., Tossios K. Gingival fibromatosis and significant tooth eruption delay in an 11 years old male: 30 months follow-up. International Journal of Paediatric Dentistry 2005; 15: 294-302.
  8. Dereka X.E., Markopoulou C.E., Mamalis A., Pepelassi E., Vrotsos I.A. Time-and dose-dependent mitogenic effect of bFGF combined with different bone graft materials. An in vitro study. Clinical Oral Implants Research 2006; 17(5): 554-559.
  9. Pepelassi E.A., Markopoulou C.E., Dereka X.E., Mamalis A.A., Vrotsos I.A.,  Koutsilieris M. Platelet-rich plasma effect on periodontally affected human gingival fibroblasts: an in vitro study. Journal of the International Academy of Periodontology 2009; 11: 160-168.
  10. Markopoulou C. E., Markopoulos P., Dereka X. E., Pepelassi E., Vrotsos I. A. Effect of homologous PRP on proliferation of human periodontally affected osteoblasts. In vitro preliminary study. Report of a case. Journal of Musculoskeletal Neuronal Interactions 2009; 9: 167-172.
  11. Tsami A., Pepelassi E., Kodovazenitis G., Komboli M. Parameters affecting tooth loss during periodontal maintenance in a Greek population. Journal of the American Dental Association 2009; 140: 1100-1107.
  12. Markou N., Pepelassi E., Vavouraki H., Stamatakis H., Nikolopoulos G., Vrotsos I., Tsiklakis K. Treatment of periodontal endosseous defects with platelet-rich plasma alone or in combination with demineralized freeze-dried bone allograft: A comparative clinical trial. Journal of Periodontology 2009; 80: 1911-1919.
  13. Kotsovilis S., Markou N., Pepelassi E., Nikolidakis D. The adjunctive use of platelet-rich plasma in the therapy of periodontal intraosseous defects: a systematic review. Journal of Periodontal Research 2010; 45: 428-443.
  14. Markou N., Pepelassi E., Kotsovilis S., Vrotsos I., Vavouraki H., Stamatakis H.C. The use of platelet-rich plasma combined with demineralized freeze-dried bone allograft in the treatment of periodontal endosseous defects: a report of two clinical cases. Journal of the American Dental Association 2010; 141(8): 967-978.
  15. Mouzakiti E., Pepelassi E., Fanourakis G., Markopoulou C., Tseleni-Balafouta S., Vrotsos I.  The effect of smoking on the mRNA expression of MMPs and TIMP-1 in untreated chronic periodontitis patients: A cross-sectional study. Journal of Periodontal Research 2011; 46 (5): 576-583.
  16. Markopoulou C.E., Dereka X.E., Vavouraki H.N., Pepelassi E.A., Mamalis A.A., I.K. Karoussis, Vrotsos I.A. Effect of rhTGF-β1 combined with bone grafts on human periodontal cell differentiation. Growth Factors 2011; 29(1): 14-20.
  17. Patsouri A., Mavrogiannea A., Pepelassi E., Gaintantzopoulou M., Kakaboura A. Clinical effectiveness of a desensitizing system on dentin hypersensitivity in periodontitis patients. American Journal of Dentistry 2011; 24(2): 85-92.
  18. Loukideli M., Tsami A., Pepelassi E., Komboli M., Doukoudakis A. Root proximity characteristics and type of alveolar bone loss: a case-control study. Journal of the International Academy of Periodontology 2011; 13(1): 73-79.
  19. Plessas A., Pepelassi E. Dental and periodontal complications of lip and tongue piercing: Prevalence and influencing factors. Australian Dental Journal  2012; 57: 71–78.
  20. Pepelassi E., Nicopoulou-Karayianni K.,  Archontopoulou A.D., Mitsea A.,  Kavadella A., Tsiklakis K., Vrotsos I., Devlin H., Horner K.. The relationship between osteoporosis and periodontitis in women aged 45–70 years. Oral Diseases 2012; 18 (4): 353-359.
  21. Mouzakiti E., Pepelassi  E., Fanourakis G., Markopoulou C., Tseleni-Balafouta S.,  Vrotsos I. Expression of MMPs and TIMP-1 in smoker and nonsmoker chronic periodontitis patients before and after periodontal treatment. Journal of Periodontal Research 2012; 47(4): 532-542.
  22. Xynogala I., Pepelassi E., Perrea D., Agrogiannis G., Pantopoulou A., Patsouris E.,  Vrotsos I.  Adiponectin and interleukin-6 levels in insulin-treated diabetic rats with experimental periodontitis. Brazilian Oral Research 2012; 26(1): 71–76.
  23. Pepelassi E., Xynogala I., Perrea D., Agrogiannis G., Pantopoulou A., Patsouris E., Vrotsos I. Histometric Assessment of the Effect of Diabetes Mellitus on Experimentally Induced Periodontitis in Rats. Journal of the International Academy of Periodontology 2012; 14(2): 35-41.
  24. Loukideli M., Tsami A., Pepelassi E., Vrotsos I. The effect of root proximity on the dimensions of the interdental space: a case control study. Indian Journal of Stomatology, Jan-March 2013.
  25. Zoumpopoulou G., Pepelassi E., Papaioannou W., Georgalaki M., Maragkoudakis P.A., Tarantilis P., Tsakalidou E., Papadimitriou K. Incidence of bacteriocins produced by food-related lactic acid bacteria active towards oral pathogens. International Journal of Mollecular Sciences 2013; 14(3): 4640-4654.

Areas of scientific interest

  • Periodontal regeneration, specifically biologic mediators of the regeneration of the periodontal tissues
  • Experimental periodontitis
  • Experimental diabetes
  • Biochemical agents implicated in periodontitis
  • Biology of the periodontium

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